Publikationen

2020 (in alphabetischer Reihenfolge)

Bobrov, Evgeny (2020) Open Data can be advanced by the COVID-19 pandemic, but will still require a comprehensive approach. Elephant in the Lab. doi.org/10.5281/zenodo.3732948

Brückner, Till (2020) Achieving excellence in clinical trial reporting, Published under a Creative Commons license (CC-BY)

Dirnagl U (2020) Preregistration of exploratory research: Learning from the golden age of discovery. PLoS Biol 18(3): e3000690. doi.org/10.1371/journal.pbio.3000690

Claudia Kurreck, Esmeralda Castaños-Vélez, Dorette Freyer, Sonja Blumenau, Ingo Przesdzing, Rene Bernard, Ulrich Dirnagl. 2020. Improving quality of preclinical academic research through auditing: A feasibility study. OSF Preprints, March 10. Preprint available here: DOI: 10.31219/osf.io/y8tpd

Elena Pavlenko, Daniel Strech, Holger Langhof Implementation of data access and use procedures in clinical data warehouses. A systematic review of literature and publicly available policies Preprint medRxiv doi.org/10.1101/2020.01.27.20018861

McCann SK, Lawrence CB. Comorbidity and age in the modelling of stroke: are we still failing to consider the characteristics of patients with stroke? BMJ Open Sci. 2020; 4:e100013. doi.org/10.1136/bmjos-2019-100013

Nico Riedel, Miriam Kip, Evgeny Bobrov. 2020. ODDPub – a Text-Mining Algorithm to Detect Data Sharing in Biomedical Publications. bioRxiv preprint: doi.org/10.1101/2020.05.11.088021

Rollwage, Max, Franziska Pannach, Caedyn Stinson, Ulf Toelch, Igor Kagan, and Arezoo Pooresmaeili. 2020. Judgments of Effort Exerted by Others Are Influenced by Received Rewards. Scientific Reports 10 (1): 1–14. doi.org/10.1038/s41598-020-58686-0.

Simons, A., Riedel, N., Toelch, U. et al. Assessing the Organizational Climate for Translational Research with a New Survey Tool. Sci Eng Ethics (2020). doi.org/10.1007/s11948-020-00234-0

Daniel Strech, Tracey Weissgerber, Ulrich Dirnagl, on behalf of QUEST Group Improving the trustworthiness, usefulness, and ethics of biomedical research through an innovative and comprehensive institutional initiative PLoS Biol. 2019 Apr 9; February 11, 2020 doi.org/10.1371/journal.pbio.3000576

Strzebonska K, Wasylewski MT, Zaborowska L, Riedel N, Wieschowski S, Strech D, Waligora M. Results dissemination of registered clinical trials across Polish academic institutions: a cross-sectional analysis BMJ Open 2020;10:e034666. doi: 10.1136/bmjopen-2019-034666

Weissgerber T et al (2020). Point of View: Mitigating the impact of conference and travel cancellations on researchers’ futures. eLife 2020;9:e57032 doi: 10.7554/eLife.57032

Wieschowski S, Laser H, Sena ES, Bleich A, Tolba R, Strech D. Attitudes towards animal study registries and their characteristics: An online survey of three cohorts of animal researchers. PLoS One. 2020 Jan 6;15(1):e0226443. doi: 10.1371/journal.pone.0226443. eCollection 2020


2019 (in alphabetischer Reihenfolge)

Bernard Rene, Tracey L. Weissgerber, Evgeny Bobrov, Stacey Winham, Ulrich Dirnagl, and Nico Riedel. 2019. Fiddle: A Tool to Combat Publication Bias by Getting Research Out of the File Drawer and into the Scientific Community. OSF Preprints. July 23. Preprint available here: doi:10.31219/osf.io/6mcu3/

Brinken, H., Kuchma, I., Kalaitzi, V., Davidson, J., Pontika, N., Cancellieri, M., Correia, A., Carvalho, J., Melero, R., Kastelic, D., Borba, F., Lenaki, K., Toelch, U., Zourou, K., Knoth, P., Schmidt, B., Rodrigues, E., 2019. A Case Report: Building communities with training and resources for Open Science trainers. LIBER Quarterly 29, 1–36. doi.org/10.18352/lq.10303www.liberquarterly.eu/articles/10.18352/lq.10303/

Bobrov, Evgeny (2019) Increasing value in biomedical research – The QUEST Center at the Berlin Institute of Health. Elephant in the Lab. doi.org/10.5281/zenodo.3360497

Caliebe A, Scherag A, Strech D, Mansmann U. Scientific and ethical evaluation of projects in data-driven medicine. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Jun;62(6):765-772. doi: 10.1007/s00103-019-02958-2. Review. German. 

Crüwell, S., van Doorn, J., Etz, A., Makel, M. C., Moshontz, H., Niebaum, J., Orben, A., Parsons, S., & Schulte-Mecklenbeck, M. (2019) 7 Easy Steps to Open Science: An Annotated Reading List. Zeitschrift für Psychologie (2019), 227, pp. 237-248. doi.org/10.1027/2151-2604/a000387. © 2019 Hogrefe Publishing. 

Crüwell, S., Stefan, A.M. & Evans, N.J. Robust Standards in Cognitive Science. Comput Brain Behav 2, 255–265 (2019). doi.org/10.1007/s42113-019-00049-8

Currie GL, Angel-Scott H, Colvin L, Cramond F, Hair K, Khandoker L, Liao J, Macleod MR, McCann SK, Morland R, Sherratt N, Stewart R, Tanriver-Ayder E, Thomas J, Wang Q, Wodarski R, Xiong R, Rice ASC, Sena ES. Animal models of chemotherapy-induced peripheral neuropathy: a machine-assisted systematic review and meta-analysis. PLOS Biology 2019 17(5): e3000243. doi.org/10.1371/journal.pbio.3000243

Dirnagl U. Rethinking research reproducibility. EMBO J. 2019 Jan 15;38(2). pii: e101117. doi: 10.15252/embj.2018101117. Epub 2018 Dec 5. No abstract available. PMID: 30518534

Dirnagl U. The p value wars (again). Eur J Nucl Med Mol Imaging. 2019 Nov;46(12):2421-2423. doi: 10.1007/s00259-019-04467-5. No abstract available. PMID:31375858

Hair K, Macleod MR, Sena ES, on behalf of the IICARus Collaboration. A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines (IICARus). Research Integrity and Peer Review 2019; 4:12. doi.org/10.1186/s41073-019-0069-3

Hardwicke Tom, Wallach Joshua, Kidwell Mallory, Ioannidis John (under review). An empirical assessment of transparency and reproducibility-related research practices in the social sciences (2014-2017). Royal Society Open Science. doi.org/10.1098/rsos.190806

Hardwicke Tom, Serghiou Stylianos, Janiaud Perrine, Danchev Valentin, Crüwell Sophia, Goodman Steven, Ioannidis John (in press). Calibrating the scientific ecosystem through meta-research. Annual Review of Statistics and its Application. Pre-print available here: doi.org/10.31222/osf.io/krb58

Hardwicke Tom, Ioannidis John P. A. (2019). Petitions in scientific argumentation: dissecting the request to retire statistical significance. European Journal of Clinical Investigation. doi:doi.org/10.1111/eci.13162

Hardwicke, T. E., Frank, M. C., Vazire, S., & Goodman, S. N. (2019). Should psychology journals adopt specialized statistical review? Advances in Methods and Practices in Psychological Science. doi.org/10.1177/2515245919858428

Ioannidis John P. A., MD, DSc. The Importance of Predefined Rules and Prespecified Statistical Analyses Do Not Abandon Significance. JAMA. Published online April 4, 2019. doi:10.1001/jama.2019.4582 

Lalu M, Fergusson DA, Cheng W, Avey MT, Corbett D, Dowlatshahi D, Macleod MR, Sena ES, Moher D, Shorr R, McCann SK, Gray L, Hill M, O'Connor A, Haggar F, Dobriyal A, Chung HS, Welton N, Hutton B. Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis. F1000Research 2019, 8:11; doi.org/10.12688/f1000research.15869.1

Nosek, B. A., Beck, E. D., Campbell, L., Flake, J. K., Hardwicke, T. E., Mellor, D. T., van ‘t Veer, A. E., & Vazire, S. (2019). Preregistration is hard, and worthwhile. Trends in Cognitive Sciences. doi: doi.org/10.1016/j.tics.2019.07.009

Piper SK, Grittner U, Rex A, Riedel N, Fischer F, Nadon R, Siegerink B, Dirnagl U. Exact replication: Foundation of science or game of chance? PLoS Biol. 2019 Apr 9;17(4):e3000188. doi: 10.1371/journal.pbio.3000188. eCollection 2019 Apr.

Ramos-Hryb AB, Bahor Z, McCann SK, Sena ES, Macleod MR, Lino de Oliveira C. Protocol for a systematic review and meta-analysis of data from preclinical studies employing the forced swimming test: an update. BMJ Open Science 2019;3:e000043; doi.org/10.1136/bmjos-2017-000043

Strech D, Dirnagl U. 3Rs missing: animal research without scientific value is unethical. BMJ Open Science 2019;3:e000048. doi: 10.1136/bmjos-2018-000048

Strech D, Sievers S, Märschenz S et al. Tracking the timely dissemination of clinical studies. Characteristics and impact of 10 tracking variables [version 1; peer review: 3 approved]. F1000Research 2018, 7:1863. doi.org/10.12688/f1000research.17022.1

The NPQIP Collaborative group. Did a change in Nature journals’ editorial policy for life sciences research improve reporting? BMJ Open Science 2019;3:e000035. doi.org/10.1136/bmjos-2017-000035

Weissgerber TL, Garcia-Valencia O, Garovic VD, Milic NM, Winham SJ. Meta-Research: Why We Need to Report More Than 'Data were Analyzed by t-tests or ANOVA'. eLife. DOI: 10.7554/eLife.36163.001

Weissgerber TL, Garovic VD. (2019) Rethinking prenatal exercise trials: How can we improve translation? Mayo Clinic Proceedings, 94(10):1951-1959. doi: 10.1016/j.mayocp.2019.08.017.

Weissgerber Tracey L. PhD, Winham Stacey J. PhD, Heinzen Ethan P., Milin-Lazovic Jelena S. MD, Garcia-Valencia Oscar MD, Bukumiric Zoran MD, PhD, Savic Marko D. MPH, Garovic Vesna D. MD, PhD, Milic Natasa M. MD, PhD Reveal, Don’t Conceal Transforming Data Visualization to Improve Transparency Circulation 2019;140:1506–1518.    DOI:10.1161/CIRCULATIONAHA.118.037777

Susanne Wieschowski, Nico Riedel, Katharina Wollmann, Hannes Kahrass, Stephanie Müller-Ohlraun, Christopher Schürmann, Sean Kelley, Ute Kszuk, Bob Siegerink, Ulrich Dirnagl, Jörg Meerpohl, Daniel Strech, Result dissemination from clinical trials conducted at German university medical centers was delayed and incomplete, Journal of Clinical Epidemiology, Volume 115, 2019, Pages 37-45, ISSN 0895-4356, doi.org/10.1016/j.jclinepi.2019.06.002

Wieschowski S, Biernot S, Deutsch S, Glage S, Bleich A, Tolba R, et al. (2019) Publication rates in animal research. Extent and characteristics of published and non-published animal studies followed up at two German university medical centres. PLoS ONE 14(11): e0223758.doi.org/10.1371/journal.pone.022375


2018 (in alphabetischer Reihenfolge)

Bossert S, Kahrass H, Strech D. The Public's Awareness of and Attitude Toward Research Biobanks - A Regional German Survey. Front Genet 2018;9:190. doi: 10.3389/fgene.2018.00190 

Dirnagl U, Kurreck C, Castaños-Vélez E, Bernard R. (2018) Quality management for academic laboratories: burden or boon? Professional quality management could be very beneficial for academic research but needs to overcome specific caveats.EMBO Rep.19. pii: e47143 

Dirnagl U, Bernard R. (2018) Error and error Management in biomedical Research. In: How could this happen? Managing errors in organisations. Editors: Hagen, Jan U. (Ed.) and Zenodo

Ulrich Dirnagl, Mark Yarborough Klinische Studien an Patientinnen und Patienten mit schwerwiegenden Hirnerkrankungen: Qualität präklinischer Evidenz im ethischen Kontext, Forschung Politik, Strategie, Management 2018;11(2+3):65.

Ives J, Dunn M, Molewijk B, et al. Standards of practice in empirical bioethics research: towards a consensus. BMC Med Ethics 2018;19(1):68. doi: 10.1186/s12910-018-0304-3 

Langhof, Holger; Schwietering, Johannes; Strech, Daniel (2018): Practice evaluation of biobank ethics and governance: current needs and future perspectives. In: Journal of Medical Genetics, doi: 10.1136/jmedgenet-2018-105617 

Langhof, Holger; Chin, William; Wieschowski, Susanne; Federico, Carole; Kimmelman, Jonathan; Strech, Daniel (2018): Preclinical efficacy in therapeutic area guidelines from the U.S. Food and Drug Administration and the European Medicines Agency: a cross-sectional study. In: British Journal of Pharmacology, doi: 10.1111/bph.14485.

Langhof H, Kahrass H, Illig T, et al. Current practices for access, compensation, and prioritization in biobanks. Results from an interview study. Eur J Hum Genet 2018 doi: 10.1038/s41431-018-0228-x 

Mc Cord KA, Al-Shahi Salman R, Treweek S, et al. Routinely collected data for randomized trials: promises, barriers, and implications. Trials 2018;19(1):29. doi: 10.1186/s13063-017-2394-5 

McLennan S, Kahrass H, Wieschowski S, et al. The spectrum of ethical issues in a Learning Health Care System: a systematic qualitative review. Int J Qual Health Care 2018;30(3):161-68. doi: 10.1093/intqhc/mzy005 

Strech D. Normative Governance der Big Data Forschung. Forschung Politik, Strategie, Management 2018;11(2+3):53-59.

Strech D, Götzelmann T. Forschungsethik bei Demenz. In: Jessen F, ed. Handbuch Alzheimer-Krankheit: Grundlagen – Diagnostik – Therapie – Versorgung – Prävention Berlin: de Gruyter 2018.

Strech D, Kahrass H. Nationale und internationale Initiativen zur Herstellung von Transparenz über Beziehungen von Ärzten zu pharmazeutischen Unternehmen In: Lieb K, Klemperer D, Kölnel R, et al., eds. Interessenkonflikte, Korruption und Complaince im Gesundheitswesen. Berlin: Medizinisch Wissenschaftliche Verlagsgesellschaft 2018:151-58.

Toelch, Ulf, and Dirk Ostwald. 2018. “Digital Open Science—Teaching Digital Tools for Reproducible and Transparent Research.” PLOS Biology 16 (7): e2006022. 

J Vollert, E Schenker, M Macleod, A Bespalov, H Wuerbel, MC Michel, U Dirnagl, H Potschka, KE Wever, T Steckler, B Altevogt, ASC Rice on behalf of the EQIPD WP3 study group. Protocol for a systematic review of guidelines for rigour in the design, conduct and analysis of biomedical experiments involving laboratory animals. BMJ Open Science 2(1). E-Pub

Susanne Wieschowski, Nico Riedel, Katharina Wollmann, Hannes Kahrass, Stephanie Mueller-Ohlraun, Christopher Schuermann, Sean Kelley, Ute Kszuk, Bob Siegerink, Ulrich Dirnagl, Joerg Meerpohl, Daniel Strech. Benchmarking university medical centres for responsible metrics. A cross sectional study on timely results dissemination across 36 German centres. Preprint BioRxiv. doi: 10.1101/467746 

Wieschowski S, Chin WWL, Federico C, et al. Preclinical efficacy studies in investigator brochures: Do they enable risk-benefit assessment? PLoS Biol 2018;16(4):e2004879. doi: 10.1371/journal.pbio.2004879 

Yarborough M, Bredenoord A, D'Abramo F, Joyce NC, Kimmelman J, Ogbogu U, Sena E, Strech D, Dirnagl U. The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials.PLoS Biol. 2018 Jun 6;16(6):e2006343


2017 (in alphabetischer Reihenfolge)

Bossert S, Kahrass H, Heinemeyer U, et al. Participatory improvement of a template for informed consent documents in biobank research - study results and methodological reflections. BMC Med Ethics 2017;18(1):78. doi: 10.1186/s12910-017-0232-7 

Bossert S, Strech D. An integrated conceptual framework for evaluating and improving 'understanding' in informed consent. Trials 2017;18(1):482. doi: 10.1186/s13063-017-2204-0 

Langhof H, Kahrass H, Sievers S, et al. Access policies in biobank research: what criteria do they include and how publicly available are they? A cross-sectional study. Eur J Hum Genet 2017;25(3):293-300. doi: 10.1038/ejhg.2016.172 

Mertz M, Strech D, Kahrass H. What methods do reviews of normative ethics literature use for search, selection, analysis, and synthesis? In-depth results from a systematic review of reviews. Syst Rev 2017;6(1):261. doi: 10.1186/s13643-017-0661-x 

Neumann K, Grittner U, Piper S, Rex A, Florez-Vargas O, Karystianis G, Schneider A, Wellwood I, Siegerink B, Ioannidis JPA, Kimmelman J, Dirnagl U (2017) Increasing efficiency of preclinical research by group sequential designs.  Plos Biol 15(3):e2001307 

Weissgerber TL, Savic M, Winham SJ, Stanisavijevic D,Garovic VD, Milic N. (2017) Data visualization, bar naked: A free tool for creating interactive graphics. Journal of Biological Chemistry 292(50):20592-20598. PMC5733595. doi 10.1074/jbc.RA117.000147 

Yarborough M, Dirnagl U. Preclinical research: Meet patients to sharpen up research.Nature. 2017 Nov 16;551(7680):300 


2016 und älter (in alphabetischer Reihenfolge)

Begley CG, Buchan AM, Dirnagl U (2015). Robust research: Institutions must do their part for reproducibility.Nature 525:25-7. 

Dirnagl U, Przesdzing I, Kurreck C, Major S. (2016) A laboratory critical incident and error reporting system for experimental biomedicine.Plos Biol 14: e2000705

Dirnagl U, Przesdzing I. (2016) A pocket guide to electronic laboratory notebooks in the academic life sciences [version 1; referees: 3 approved] F1000Research 2016, 5:2 doi: 10.12688/f1000research.7628.1 

Weissgerber TL, Garovic VD, Milin-Lazovic JS, Winham SJ, Obradovic Z, Trzeciakowski JP, Milic NM. (2016) Re-inventing Biostatistics Education for Basic Scientists.PLOS Biology, 14(4):e1002430, PMC4825954. 

Weissgerber TL, Garovic VD, Savic M, Winham SJ, Milic NM. (2016) From Static to Interactive: Transforming Data Visualization to Improve Transparency.PLOS Biology 14(6):e1002484, PMC4917243. 

Weissgerber TL, Garovic VD, Winham SJ, Milic NM, Prager EM. (2016) Transparent Reporting for Reproducible Research (Editorial).Journal of Neuroscience Research 94(10):859-864. 

Weissgerber TL, Milic NM, Winham SJ, Garovic VD. (2015) Beyond Bar and Line Graphs: Time for a New Data Presentation Paradigm.PLOS Biology, 13(4):e1002128, PMC4406565.