BIH Lecture Series: Frontiers in Translational Medicine - Scientific and Structural Challenges

During the winter semester 2019/20 the BIH starts off the new lecture series "Frontiers in Translational Medicine - Scientific and Structural Challenges" on key questions of translation in medicine. The series features lunchtime discussions with leading personalities from translational research. How must a translational ecosystem be set up, and what can we learn from international best practices? How can the success of translation be measured in the first place and how can the science system implement appropriate criteria in order to entice researchers? On Fridays at lunchtime, BIH invites an internationally renowned expert to give a lecture on these and other questions, followed by discussion and networking with the community.

Lecture 12: "Keys to Successfull Technology Translation by Entrepeneurs in Academia and Biotech"

On 11 December 2020 Angelika Fretzen was a speaker at the BIH Lecture Series. She is Technology Translation Director, COO Wyss Institute for Biologically Inspired Engineering at Harvard University. The Wyss Institute for Biologically Inspired Engineering at Harvard University has developed a unique model that takes the most innovative ideas from 'blue sky' research by leading academic groups in the Boston area and translates them into risk-free technologies.

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Lecture 11: "Cerebral Organoids - Modeling Human Development and Disease"

On November 27, 2020, Jürgen Knoblich gave a talk at the BIH Lecture Series. He is Senior Scientist and Scientific Director of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences - IMBA. In his research group he is investigating cerebral organoids to recapitulate diseases of the human brain in vitro and to test risk factors. Cerebral organoids derived from patients suffering from a neurological developmental disorder can recapitulate the developmental defects leading to these diseases and allow us to unravel the mechanistic complexity of disorders such as epilepsy and autism.

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Lecture 10: "Metabolic Aspects of Angiogenesis in Physiology and Disease"

On 30 October 2020 Michael Potente was speaker in the BIH Lecture Series. He is BIH Professor for Translational Vascular Biomedicine and spoke about the influence of metabolic processes on the formation of blood vessels in health and disease. Aberrant angiogenesis is a characteristic and trigger of cancer or inflammation, but therapeutic approaches have so far shown little success. New insights into the metabolic processes that small blood vessels use to form networks open up new possibilities for intervention.

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Lecture 9: "The BIH - an Institute Dedicated to the Science of Translation"

On 2 October 2020, the new BIH CEO Professor Christopher H. Baum took office and took the opportunity to speak at our BIH Lecture Series. His lecture dealt with BIH and the question of how translational medicine and a science of translation can succeed.

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Lecture 8: "Frontiers in Translational Medicine - An Industry Perspective"

On 31 July 2020 Florian Gantner was guest in our BIH Lecture Series. He is Senior Vice President Translational Medicine & Clinical Pharmacology at C.H. Boehringer Sohn AG & Co. KG and gave a lecture on the industrial view on the scientific and structural challenges of translation.

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Lecture 7: "How to Create a Scientific Spin-off"

On 5 June 2020 Sonja Jost was a guest in our BIH Lecture Series. She is CEO of the start-up company DexLeChem and spoke in her lecture about the ways and possibilities to apply scientific knowledge about a start-up company. The seventh session of the Lecture Series was the second one that we offered completely as video conference.

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Lecture 6: "What does it take to translate? - Lessons Learned in Regenerative Medicine

On 27 March 2020 Prof. Georg N. Duda gave an insight into the experiences of the BIH Center for Regenerative Therapies (BCRT) with translation in regenerative medicine. He is co-speaker of the BCRT and director of the Julius-Woff-Institute for Biomechanics and Musculoskeletal Regeneration at the Charité - Universitätsmedizin Berlin. The sixth lecture of the series was also a premiere - in the time of the COVID 19 pandemic it was the first lecture organized by the BIH as a video conference with about 170 participants*.

Lecture in video

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Lecture 5: "Translating Data into Health - Clinical Translationl Research in the Digital Age

On February 28, 2020, Prof. Christof von Kalle gave an introduction to the challenges of Clinical Translational Research in the Digital Age. He is BIH-Chair for Clinical Translational Sciences and Director of the Clinical Study Center of the BIH and Charité - Universitätsmedizin Berlin. At our fifth session of the lecture series "Frontiers in Translational Medicine - Scientific and Structural Challenges" he spoke on "Translating Data into Health - Clinical Translational Research in the Digital Age".

Lecture in video

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Lecture 4: "From infection research to new antiviral drugs

On 14 February 2020, Prof. Susanne Herold presented the perspective of Clinician Scientists on translational research. She is Professor of Lung Diseases at the University Hospital Gießen-Marburg, where she heads the Department of Infectiology. At our fourth session of the lecture series "Frontiers in Translational Medicine - Scientific and Structural Challenges" she spoke on the topic "From infection research to new antiviral drugs" and gave an insight into her current research.

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Lecture 3: "Immunological Challenges of Regenerative Therapies - what, why, how?"

On 31 January 2020, the BIH again invited participants to reflect and discuss the challenges of translational research in the historic Virchow lecture hall of the Charité – Universitätsmedizin Berlin. At the third lecture of the series and the first one this year, Prof. Hans-Dieter Volk, speaker of the BIH Center for Regenerative Therapies, spoke on the topic "Immunological Challenges of Regenerative Therapies - what, why, how?"

Lecture in video

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Lecture 2: "Debunking Common Myths about Translation"

On 22 November 2019 the BIH invited to the second lecture of the series. Professor Ulrich Dirnagl, founding director of the BIH QUEST Center, spoke on "Debunking Common Myths about Translation". He argued that, over the last twenty years, ideas of translation have become ingrained that were not true and distracted from different or even better approaches to translation medicine.

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Lecture 1: "Frontiers in Translational Medicine - Scientific and Structural Challenges"

Professor Axel Radlach Pries, Chairman of the BIH Board (interim) and Dean of the Charité - Universitätsmedizin, opened the new lecture series on 8 November 2019 in the Hans Virchow lecture hall of the Charité Campus Mitte.  With questions and answers on the structures and conditions of successful translational medicine, he addressed all those interested in translation and the work of BIH. 

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