RE-PLACE studies the process of shifting from analogue documentation of research processes in paper lab books to so-called electronic laboratory notebooks (ELN). ELNs do not only digitalize the documentation of researchers’ experiments, but also link their notes directly to research data generated in experiments. On the initiative of BIH QUEST Center, the Berlin Institute of Health (BIH) is currently implementing an institutional programme to replace analogue research documentations with ELN Labfolder. To evaluate this implementation process, Charité - Universitätsmedizin Berlin together with Otto-von-Guericke-University Magdeburg started the BMBF-funded research project RE-PLACE in August 2020. RE-PLACE aims at assessing the overall value and benefits of adopting ELN Labfolder at BIH.