The BIH QUEST Center for Transforming Biomedical Research

QUEST – Quality | Ethics | Open Science | Translation


Mission Statement

QUEST strives to increase the value of biomedical research at BIH and beyond.

Our Mission

To overcome the roadblocks in translational medicine: Increasing the value and impact of biomedical research by maximizing the quality, reproducibility, generalizability, and validity of BIH research.
To create an awareness of the need to rethink biomedical research and to initiate a culture change in academic biomedicine.

Our Approaches

Quality assurance

We promote compliance of preclinical as well as clinical research with standards and guidelines on design, conduct, analysis and reporting.

Further information

Education & Training

We develop and implement training and teaching resources on experimental and study design, methods to reduce bias, new modes of publishing, the digital footprint of academics, as well as open science.

Further information

Open Science

We increase the accessibility and transparency of BIH research through Open Data and promote research data management.

Further information

Meta Research

We identify opportunities for improving research practice and obtain evidence for the impact of its activities through ‘research on research’.

Further information

Incentives and rewards

We develop new incentive systems in research, e.g. by selecting appropriate novel indicators and metrics for the assessment of research performance of researchers and institutions.

Further information

Stakeholder Engagement

We develop, support and evaluate Patient and Stakeholder Engagement activities throughout the entire process of biomedical research.

Further information

Translational Bioethics

We develop evidence-based and practice-oriented recommendations on how ethical requirements for research with humans, animals and sensitive data can be best implemented.

Further information


We act as advisors to stakeholders in biomedicine from funders to politics.