The BIH QUEST Center has recently become a CAMARADES National Coordinating Center. CAMARADES (Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies) are leaders in the field of preclinical systematic review and meta-analysis. These meta-research tools can serve a number of functions in translational biomedicine, including to identify potential sources of bias and other barriers to translation in animal studies; inform recommendations for improvements in the design and reporting of animal experiments; and inform selection of candidate interventions for advanced preclinical or clinical trials.
CAMARADES provide a supporting framework for researchers involved in the review of data from experimental animal studies, including best practice methodological assistance and access to collaborative tools such as our online review facility, SyRF. Our research involves developing and implementing automation tools, including machine learning and text mining, to streamline preclinical systematic reviews, improving the speed and accuracy with which they can be completed. We aim to provide a central focus for data sharing and currently act as a public repository for review protocols and completed reviews.
We warmly welcome enquiries from researchers interested in learning more about preclinical systematic review and meta-analysis or starting their own review. We also offer hands-on workshops for student or research groups. Please contact Dr. Sarah McCann.