BIH/Charité Clinical Study Center

The Clinical Study Center (CSC) is the interdisciplinary and cross-campus platform for clinical studies at BIH. It aims to continuously develop and network translational medical system research activities at MDC and Charité.

The CSC is integrated into the BIH platform "Clinical Translational Sciences", and is active at all Charité sites. At these sites, research and treatment take place under one roof: Participating researchers and clinicians have access to treatment stations, examination rooms and research labs, as well as to their own administration and documentation. This enables complementary expertise to be integrated into a common translational research area.

Our goal is to advance health-oriented translational sciences by supporting innovative and interdisciplinary projects. In doing so, we focus on developing cohorts and implementing hypothesis-driven projects.

An overview of our services can be found here.

If you would like to use the services of the CSC, please contact a coordinator at your location as a first step.

We carry out clinical research projects in accordance with high quality standards based on national and international guidelines. We also provide a core facility for clinical researchers within the Charité and the MDC, creating a network of different fields of expertise and existing structures. Over the next few years, we plan to further expand and deepen this network. We are working to achieve a pioneering role in the national and international research landscape, including institutions not involved in BIH.

As CSC researchers, we are transparent and innovative. Our collaboration is built on mutual respect and continuous personnel development, and we emphasize the importance of input by all team members. We are guided by evidence-based medicine and international scientific standards. In decision-making processes, our patients’ wellbeing and the independence of our research are of paramount importance.

In order to meet our high quality standards, we have instituted a quality management system (QMS) that monitors all activities surrounding implementation of clinical research projects by CSC. This includes activities involving phenotyping of patients; those related to the service structures offered by CSC such as biosampling, laboratory management, and biostatistics; and internal administrative processes.

Neuroscience Clinical Reseach Unit

Together with NeuroCure, a cluster of excellence at the Charité - Universitätsmedizin Berlin, the BIH is establishing the Neuroscience Clinical Research Unit (Neuroscience-CRU), thus consolidating the network of translational systems medical research for the neurosciences. BIH offers direct access to a large number of preclinical, translational and clinical studies, some of which have already found their way into medical guidelines.

The neurological and psychiatric units of the Clinical Study Center of the BIH operate together with the infrastructure of the NeuroCure Clinical Research Center and will be supplemented by further modules in the future: In the new BrainLab, researchers* will work closely with the clinical areas of neurosurgery and the neurological intensive care unit and, in particular, develop treatment options for acute diseases. In the best case scenario, early therapy can prevent these diseases from progressing seriously or even leading to death.

BIH and NeuroCure are recruiting two junior research groups to set up the Neuroscience-CRU. They work independently and are also responsible for the structure and implementation of the BrainLabs. The junior research groups carry out research at the interface between clinical care and basic science: they are in contact with inpatients with acutely seriously ill patients involving the operating theatre, emergency room, intensive care unit and imaging and have access to human material for research.

  • The first junior research group will focus on computational neurology. It will develop new diagnostic methods and improved therapies using multimodal data sets and prediction methods.
  • The second junior research group will focus on the topic of subcellular optogenetics and will gain insights into neuronal networks in human tissue and their comparison with different animal models.

In the new Neuroscience-CRU, all neuroscientific studies are centrally organized, allowing researchers to benefit from the joint competence of BIH and Charité for their research work. The BIH is thus taking a further step on the path of translation, i.e. the more efficient transfer of research results into clinical application.