Our DFG-Emmy Noether Program-funded lab has two main focuses: First, we are developing in vivo tissue regeneration as a therapeutic strategy. Second, we aim to understand the dynamics between hematopoietic and hepatic systems in development and disease using blood-liver organoids.
Our lab is made up of bioinformaticians, computer scientists, ontologists, curators, and software engineers. Our mission is to develop software resources and algorithms to improve human health. Our research focuses on the development of ontologies and software for translational genomics.
The research group Model Systems for Regenerative Therapies leverages interdisciplinary approaches to interdisciplinary and translational research. Our goal is to improve our mechanistic pathophysiological understanding regarding musculoskeletal fibrosis to a level where we can offer effective solutions for clinical applications.
Through the development and implementation of science-based tools and policies, the group contributes to the alignment of internal administration and governance processes of incentives and research assessments with responsible research and innovation (RRI) as well as open sciences practices. The goal is to transfer best practice and knowledge into…
The Poikela group aims at understanding patients’ views on privacy and strengthening trust through innovative privacy-enhancing solutions in order to support the patients’ willingness to disclose data for medical research, and to enhance adoption of digital health solutions. The work takes the form of patient-centric design of privacy-enhancing…
Infectious diseases remain one of the major causes of death world-wide. Emerging infections, such as the COVID-19 pandemic or the MPVX outbreak, but also the dramatic increase in antibiotic resistance illustrate the urgent need for novel antimicrobial interventions. Vaccines represent one of the most powerfull, safe and cost-effective tools to…
Additive manufacturing (AM) technologies could be the leverage for the generation of precise and personalized scaffold constructs enabling improved bone regeneration and remodeling outcomes. Our team strives to develop methodologies and generate knowledge that could lead to mechanistic understanding of scaffold-guided bone defect regeneration…
The objective of our research group is to acquire the basic knowledge necessary to develop new therapies against diseases affecting the liver. For that, we use stem cells to model embryonic development in vitro and to produce liver cells with an interest for cell therapy.
Systematic review and meta-analysis are research synthesis methods that clearly identify what we currently know, how reliable the evidence is, and where future research is needed. Using these tools, the “Preclinical systematic reviews and meta analyses” group aims to improve the validity, increase the value, and facilitate the translation of…
We sequence cells to understand how genetic mutations form and change cell states in health and disease.