COReS Seminar Series – Emerging trends in systematic reviews for 3R principles

Course description

A systematic review uses a transparent and structured approach to identify and evaluate results of existing studies on a research question. Systematic reviews are a powerful tool to assess the accumulating evidence in biomedical research. As such, systematic reviews can help us address specific research questions and be used to directly inform the classical 3Rs principles in animal research – Replacement, Reduction, Refinement. 

Systematic reviews themselves are considered animal-free innovations as they can lead to new results and scientific insights without performing additional animal studies. They can help prevent unnecessary duplication by comprehensively summarizing what has been done already as well as help us to choose the optimal animal model for our research questions. Systematic reviews can help us make evidence-informed decisions for animal research, including informing sample size calculations and refining experiments conduct, as well as supporting translational decisions. If you are interested to learn more about evidence synthesis, visit the COReS About Synthesis website section. 

The conduct of systematic reviews to support animal research is increasing in popularity and advances and techniques are developing rapidly. This seminar series showcases emerging trends on systematic reviews of animal studies. During each session, an expert guest speaker will provide insights into their work in this space, showcasing specific tools, approaches and resources and sharing cutting edge ideas. 

Further information

COReS-Projekt