Julius Wolff Institute (JWI) - Center for Musculoskeletal Biomechanics and Regeneration
Following in the tradition of Julius Wolff, we explore the interplay between mechanics and biology in bone and muscle. Motivated by clinical necessities, we concentrate on basic and applied research in orthopedics and trauma surgery.
To the JWI website (charite.de)
In the tradition of Julius Wolff
The institute stands in the tradition of Julius Wolff, the founder of the orthopedic clinic in the Charité. The theory of Julius Wolff – the so-called "Wolff's law" – shows the correlation between mechanics and medicine, and explains that the form and structure of bone constantly adapts to mechanical loading. Wolff's law is still highly relevant for musculoskeletal research today.
Research inspired by Julius Wolff
Using Wolff's findings as a basis, we strudy the influence how biology is affected by mechanical stimulation. For example, we study stresses and strains on the musculoskeletal system of patients and athletes. Furthermore, we are investigating the regeneration processes of bone, cartilage, muscles and ligaments and analyze the loads acting on joints and bones during these processes.
Research Networks
The Julius Wolff Institute plays a significant role in various research networks and it was instrumental for the development and establishment of several research networks. Beside basic research, these networks join also translation research activities for the clinical practice. The networks focus their research activities on Musculoskeletal Disease and Disorders and Regenerative Therapies.
Translation of research into clinical practice
Our research benefits patient care and stimulates innovations for implants in the area of joint replacement as well as fracture healing. Through a better understanding of biological processes during healing, we were able to develop new therapies and products for accelerating healing processes. In order to translate our findings into practice we closely collaborate with national and international partners from industry and science.
Clinical Cooperation
In order to translate our findings into practice we have a close partnership with the Center for Musculoskeletal Surgery. The center provides the highest medical care to national and international patients at a university level. The medical experts cover surgeries as well as conservative treatments and offer the whole spectrum of modern orthopedic, traumatological and reconstructive surgery.
