Digital Health

Contact information
Address:	Luisenstr. 65 10115 Berlin
Phone:	+49 30 450 543 084
E-mail:	roland.eils@bih-charite.de

Roland Eils is also heading the Hub for Innovations in Digital Health, HiDiH, a joint collaboration of his BIH unit and the Health Data Science Unit at the Medical Faculty of Heidelberg University. In addition, Roland Eils is an active member of the Medical Informatics Initiative, where he has founded and coordinated HiGHmed. HiGHmed brings together 10 university medical centers for developing interoperable solutions and infrastructures for processing and sharing of clinical and translational research data.

Artificial Intelligence - ailslab

Roland Eils has assembled a small but highly innovative team of students and scientists venturing into different aspects of digital health. The ailslab focusses on innovative methods from the wider field of artificial intelligence for pioneering digital health applications. At the heart of this lab is the integration of huge and deep datasets from both healthcare and research for tackling pressing issues in health and disease. The ambition is to deepen our understanding of disease mechanisms and to improve diagnosis and treatment of cardiovascular and cancer patients among others. Current projects focus on cardiovascular risk modelling, omni-genetic phenotype models, and building computational frameworks with model-to-data approaches for opening medical data for research purposes. Please visit https://www.hidih.org/research/ailslab for further details.

- Trump, S.*, Lukassen, S.*, Anker, M.S.*, Chua, R.L.*, Liebig, J.*, Thurmann, L.*, Corman, V.M.*, Binder, M.*, Loske, J., Klasa, C., Krieger, T., Hennig, B.P., Messingschlager, M., Pott, F., Kazmierski, J., Twardziok, S., Albrecht, J.P., Eils, J., Hadzibegovic, S., Lena, A., Heidecker, B., Burgel, T., Steinfeldt, J., Goffinet, C., Kurth, F., Witzenrath, M., Volker, M.T., Muller, S.D., Liebert, U.G., Ishaque, N., Kaderali, L., Sander, L.E., Drosten, C., Laudi, S.^§, Eils, R.^§, Conrad, C.^§, Landmesser, U.^§, & Lehmann, I.^§ (2020). Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19. Nature Biotechnology doi: 10.1038/s41587-020-00796-1
- Chua, R.L.*, Lukassen, S.*,Trump, S.*, Hennig, B.P.*, Wendisch, D.*, Pott, F., Debnath, O., Thürmann, L., Kurth, F., Völker, M.T., Kazmierski, J., Timmermann, B., Twardziok, S., Schneider, S., Machleidt, F., Müller-Redetzky, H., Maier, M., Krannich, A., Schmidt, S., Balzer, F., Liebig, J., Loske, J., Suttorp, N., Eils, J., Ishaque, N., Liebert, U.G., von Kalle, C., Hocke, A., Witzenrath, M., Goffinet, C., Drosten, C., Laudi, S.^§,Lehmann, I., Conrad, C.^§, Sander, L.-E.^§& Eils, R.^§ (2020). COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. Nature Biotechnology doi: 10.1038/s41587-020-0602-4
- Lukassen, S.*, Chua, R. L.*, Trefzer, T.*, Kahn, N.C.*, Schneider, M.A.*, Muley, T., Winter, H., Meister, M., Veith, C., Boots, A.W., Hennig, B.P., Kreuter, M.^§, Conrad, C.^§, & Eils, R.^§ (2020). SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. EMBO Journal, 39(10), doi: 10.15252/embj.20105114
- Upmeier zu Belzen, J., Bürgel, T., Holderbach, S., Bubeck, F., Adam, L., Gandor, C., Klein, M., Mathony, J., Pfuderer, P. L., Platz, L., Przybilla, M., Schwendemann, M., Heid, D., Hoffmann, M. D., Jendrusch, M., Schmelas, C., Waldhauer, M., Lehmann, I., Niopek, D.^§ & Eils, R.^§ (2019). Leveraging implicit knowledge in neural networks for functional dissection and engineering of proteins. Nature Machine Intelligence 1, 225-235. doi: 10.1038/s42256-019-0049-9
- Zapatka, M.*, Borozan, I.*, Brewer, D.S.*, Iskar, M.*, Grundhoff, A., Alawi, M., Desai, N., Cooper, C.S., Eils, R., Ferretti, V. & Lichter, P.^§ (2020). The landscape of viral association in human cancers. Nature Genetics, doi: 10.1101/465757
- Liu, L.*, Liu, C.*, Quintero, A.*, Wu, L*., Yuan, Y.*, Wang, M., Cheng, M., Leng, L., Xu, L., Dong, G., Li, R., Liu, Y., Wei, X., Xu, J., Chen, X., Lu, H., Chen, D., Wang, Q., Zhou, Q., Lin, X., Li, G., Liu, S., Wang, Q., Wang, H., Fink, J.L., Gao, Z., Liu, X., Hou, Y., Zhu, S., Yang, H., Ye, Y., Lin, G., Chen, F., Herrmann, C., Eils, R.^§, Shang, Z.^§ & Xu, X.^§ (2019). Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity. Nature Communications, 10(1), 470. doi: 10.1038/s41467-018-08205-7
- Northcott, P. A.*, Buchhalter, I.*, Morrissy, A. S.*, Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M., Zapatka, M., Jäger, N., Chavez, L., Hutter, B., Bieg, M., Paramasivam, N., Heinold, M., Gu, Z., Ishaque, N., Jäger-Schmidt, C., Imbusch, C. D., Jugold, A., Hübschmann, D., Risch, T., Amstislavskiy, V., Gonzalez, F. G. R., Weber, U. D., Wolf, S., Robinson, G. W., Zhou, X., Wu, G., Finkelstein, D., Liu, Y., Cavalli, F. M. G., Luu, B., Ramaswamy, V., Wu, X., Koster, J., Ryzhova, M., Cho, Y. J., Pomeroy, S. L., Herold-Mende, C., Schuhmann, M., Ebinger, M.,   Liau, L. M., Mora, J., McLendon, R. E., Jabado, N., Kumabe, T., Chuah, E., Ma, Y., Moore, R. A., Mungall, A. J., Mungall, K. L., Thiessen, N., Tse, K., Wong, T., Jones, S. J. M., Witt, O., Milde, T., Von Deimling, A., Capper, D., Korshunov, A., Yaspo, M. L., Kriwacki, R., Gajjar, A., Zhang, J., Beroukhim, R., Fraenkel, E., Korbel, J. O., Brors, B., Schlesner, M., Eils, R.^§, Marra, M. A.^§, Pfister, S. M.^§, Taylor, M. D.^§ & Lichter, P.^§ (2017). The whole-genome landscape of medulloblastoma subtypes. Nature. 2017 Jul 19;547(7663):311-317. doi: 10.1038/nature22973
- Bauer, T.*, Trump, S.*, Ishaque, N.*, Thurmann, L.*, Gu, L.*, Bauer, M.*, Bieg, M., Gu, Z.G., Weichenhan, D., Mallm, J.P., Roder, S., Herberth, G., Takada, E., Mucke, O., Winter, M., Junge, K.M., Grutzmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Georg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C.*, Eils, R.^§ & Lehmann, I.^§ (2016). Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Molecular Systems Biology, 12(3). doi: 10.15252/msb.20156520
- Jäger, N., Schlesner, M., Jones, David T.W., Raffel, S., Mallm, J.-P., Junge, Kristin M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., Northcott, Paul A., Korshunov, A., Drews, Ruben M., Koster, J., Versteeg, R., Richter, J., Hummel, M., Mack, Stephen C., Taylor, Michael D., Witt, H., Swartman, B., Schulte-Bockholt, D., Sultan, M., Yaspo, M.-L., Lehrach, H., Hutter, B., Brors, B., Wolf, S., Plass, C., Siebert, R., Trumpp, A., Rippe, K., Lehmann, I., Lichter, P., Pfister, Stefan M. & Eils, R.^§ (2013). Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer. Cell, 155(3), 567-581. doi: 10.1016/j.cell.2013.09.042
- Kohler, S., Boscá, D., Kärcher, F., Haarbrandt, B., Prinz, M., Marschollek, M., & Eils, R. (2023). Eos and OMOCL: Towards a seamless integration of openEHR records into the OMOP Common Data Model. Journal of Biomedical Informatics, 144. doi:ARTN 10443710.1016/j.jbi.2023.104437
- Ten, F. W., Yuan, D., Jabareen, N., Phua, Y. J., Eils, R., Lukassen, S., & Conrad, C. (2023). resVAE ensemble: Unsupervised identification of gene sets in multi-modal single-cell sequencing data using deep ensembles. Front Cell Dev Biol, 11, 1091047. doi:10.3389/fcell.2023.1091047
- Buergel, T., Steinfeldt, J., Ruyoga, G., Pietzner, M., Bizzarri, D., Vojinovic, D., Upmeier Zu Belzen, J., Loock, L., Kittner, P., Christmann, L., Hollmann, N., Strangalies, H., Braunger, J. M., Wild, B., Chiesa, S. T., Spranger, J., Klostermann, F., van den Akker, E. B., Trompet, S., Mooijaart, S. P., Sattar, N., Jukema, J. W., Lavrijssen, B., Kavousi, M., Ghanbari, M., Ikram, M. A., Slagboom, E., Kivimaki, M., Langenberg, C., Deanfield, J., Eils, R., & Landmesser, U. (2022). Metabolomic profiles predict individual multidisease outcomes. Nat Med, 28(11), 2309-2320. doi:10.1038/s41591-022-01980-3
- Loske, J., Rohmel, J., Lukassen, S., Stricker, S., Magalhaes, V., Liebig, J., Chua, R., Thurmann, L., Messingschlager, M., Seegebarth, A., Timmermann, B., Klages, S., Ralser, M., Sawitzki, B., Sander, L., Corman, V., Conrad, C., Laudi, S., Binder, M., Trump, S., Eils, R., Mall, M. A., & Lehmann, I. (2022). Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children. Nat Biotechnol, 40(3), 319-+. doi:10.1038/s41587-021-01037-9
- Pietzner, M., Chua, R. L., Wheeler, E., Jechow, K., Willett, J. D. S., Radbruch, H., Trump, S., Heidecker, B., Zeberg, H., Heppner, F. L., Eils, R., Mall, M. A., Richards, J. B., Sander, L. E., Lehmann, I., Lukassen, S., Wareham, N. J., Conrad, C., & Langenberg, C. (2022). ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19. Nat Commun, 13(1), 4484. doi:10.1038/s41467-022-31999-6
- Prokosch, H. U., Bahls, T., Bialke, M., Eils, J., Fegeler, C., Gruendner, J., Haarbrandt, B., Hampf, C., Hoffmann, W., Hund, H., Kampf, M., Kapsner, L. A., Kasprzak, P., Kohlbacher, O., Krefting, D., Mang, J. M., Marschollek, M., Mate, S., Muller, A., Prasser, F., Sass, J., Semler, S., Stenzhorn, H., Thun, S., Zenker, S., & Eils, R. (2022). The COVID-19 Data Exchange Platform of the German University Medicine. Stud Health Technol Inform, 294, 674-678. doi:10.3233/SHTI220554
- Steinfeldt, J., Buergel, T., Loock, L., Kittner, P., Ruyoga, G., Zu Belzen, J. U., Sasse, S., Strangalies, H., Christmann, L., Hollmann, N., Wolf, B., Ference, B., Deanfield, J., Landmesser, U., & Eils, R. (2022). Neural network-based integration of polygenic and clinical information: development and validation of a prediction model for 10-year risk of major adverse cardiac events in the UK Biobank cohort. Lancet Digit Health, 4(2), e84-e94. doi:10.1016/S2589-7500(21)00249-1
- Landmesser, U., Lehmann, I., & Eils, R. (2021). Hyperinflammation as underlying mechanism predisposing patients with cardiovascular diseases for severe COVID-19. European Heart Journal, 42(18), 1720-1721. doi:10.1093/eurheartj/ehab191
*these authors contributed equally.   ^§corresponding author
For a full publication list, please click here.

Computational Oncology

Naveed Ishaque recently started his own research group in the BIH unit of Roland Eils with research focus on applying computational approaches to understanding the basis of molecular biological heterogeneity in -omics data of human disease. They employ artificial intelligence and data science methods, not only to address the underlying causes of this heterogeneity, but also the interactions between different molecular -omics layers. The team has a strong specialization in the application area of oncology, but is also very interested in immunology and neurodegenerative diseases.

A better understanding of global and local patterns in biological data allows for better differentiation of the mechanistics behind biological and molecular processes from technical noise. As such, the team establishes close ties with experimental collaborators who are able to provide large-scale and high-dimensional datasets profiled using state-of-the-art and exotic profiling techniques, including recent technological advances that are able to resolve single cell, spatial, temporal and genetic heterogeneity.

Please visit https://www.hidih.org/research/computational-oncology for further details on ongoing projects in cancer multiomics and precision oncology, Immunology and allergies, or spatially resolved transcriptomics.

- Nina Hensel*, Zuguang Gu*, Sagar*, Dominik Wieland, Katharina Jechow, Janine Kemming, Sian Llewellyn-Lacey, Emma Gostick, Oezlem Sogukpinar, Florian Emmerich, David A. Price, Bertram Bengsch, Tobias Boettler, Christoph Neumann-Haefelin, Roland Eils, Christian Conrad, Ralf Bartenschlager, Dominic Grün, Naveed Ishaque^§, Robert Thimme^§ & Maike Hofmann^§ (2021). Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection. Nature Immunology https://doi.org/10.1038/s41590-020-00817-w
- Trump, S.*, Lukassen, S.*, Anker, M.S.*, Chua, R.L.*, Liebig, J.*, Thurmann, L.*, Corman, V.M.*, Binder, M.*, Loske, J., Klasa, C., Krieger, T., Hennig, B.P., Messingschlager, M., Pott, F., Kazmierski, J., Twardziok, S., Albrecht, J.P., Eils, J., Hadzibegovic, S., Lena, A., Heidecker, B., Burgel, T., Steinfeldt, J., Goffinet, C., Kurth, F., Witzenrath, M., Volker, M.T., Muller, S.D., Liebert, U.G., Ishaque, N., Kaderali, L., Sander, L.E., Drosten, C., Laudi, S.^§, Eils, R.^§, Conrad, C.^§, Landmesser, U.^§, & Lehmann, I.^§ (2020). Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19. Nature Biotechnology doi: 10.1038/s41587-020-00796-1
- Ahmed Sadik*, Luis F Somarribas Patterson*, Selcen Öztürk*, Soumya R Mohapatra, Verena Panitz, Philipp F Secker, Pauline Pfänder, Stefanie Loth, Heba Salem, Mirja Tamara Prentzell, Bianca Berdel, Murat Iskar, Erik Faessler, Friederike Reuter, Isabelle Kirst, Verena Kalter, Kathrin I Foerster, Evelyn Jäger, Carina Ramallo Guevara, Mansour Sobeh, Thomas Hielscher, Gernot Poschet, Annekathrin Reinhardt, Jessica C Hassel, Marc Zapatka, Udo Hahn, Andreas von Deimling, Carsten Hopf, Rita Schlichting, Beate I Escher, Jürgen Burhenne, Walter E Haefeli, Naveed Ishaque, Alexander Böhme, Sascha Schäuble, Kathrin Thedieck, Saskia Trump^§, Martina Seiffert^§, Christiane A Opitz^§ (2020). IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression. Cell https://doi.org/10.1016/j.cell.2020.07.038
- Park, J.*, Choi, W.*, Tiesmeyer, S., Long, B., Borm, L.E., Garren, E., Nguyen, T.N., Codeluppi, S., Schlesner, M., Tasic, B., Eils, R.^§ & Ishaque, N.^§ (2019). Segmentation-free inference of cell types from in situ transcriptomics data. bioRxiv, doi: 10.1101/800748
- Mallm, J.-P.*, Iskar, M.*, Ishaque, N.*, Klett, L.C., Kugler, S.J., Muino, J.M., Teif, V.B., Poos, A.M., Großmann, S., Erdel, F., Tavernari, D., Koser, S.D., Schumacher, S., Brors, B., König, R., Remondini, D., Vingron, M., Stilgenbauer, S., Lichter, P., Zapatka, M., Mertens, D.^§ & Rippe, K.^§ (2019). Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks. Molecular Systems Biology, 22;15(5):e8339. doi: 10.15252/msb.20188339
- Ishaque, N.*, Abba, M.L.*, Hauser, C., Patil, N., Paramasivam, N., Huebschmann, D., Leupold, J.H., Balasubramanian, G.P., Kleinheinz, K., Toprak, U.H., Hutter, B., Benner, A., Shavinskaya, A., Zhou, C., Gu, Z., Kerssemakers, J., Marx, A., Moniuszko, M., Kozlowski, M., Reszec, J., Niklinski, J., Eils, J., Schlesner, M., Eils, R., Brors, B. & Allgayer, H.^§ (2018). Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer. Nature Communications, 9(1), 4782. doi: 10.1038/s41467-018-07041-z
- Zuguang Gu, Roland Eils, Matthias Schlesner & Naveed Ishaque (2018). EnrichedHeatmap: an R/Bioconductor package for comprehensive visualization of genomic signal associations. BMC Bioinformatics https://doi.org/10.1186/s12864-018-4625-x
- Tiesmeyer, S., Sahay, S., Muller-Botticher, N., Eils, R., Mackowiak, S. D., & Ishaque, N. (2022). SSAM-lite: A Light-Weight Web App for Rapid Analysis of Spatially Resolved Transcriptomics Data. Frontiers in Genetics, 13, 7. doi:10.3389/fgene.2022.785877
- Krieger, T. G., Le Blanc, S., Jabs, J., Ten, F. W., Ishaque, N., Jechow, K., Debnath, O., Leonhardt, C. S., Giri, A., Eils, R., Strobel, O., & Conrad, C. (2021). Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy. Nat Commun, 12(1), 13. doi:10.1038/s41467-021-26059-4
- Park, J., Choi, W., Tiesmeyer, S., Long, B., Borm, L. E., Garren, E., Nguyen, T. N., Tasic, B., Codeluppi, S., Graf, T., Schlesner, M., Stegle, O., Eils, R., & Ishaque, N. (2021). Cell segmentation-free inference of cell types from in situ transcriptomics data. Nat Commun, 12(1), 13. doi:10.1038/s41467-021-23807-4

Health Data

The Heath Data team focusses on processes in medical informatics and bioinformatics. The team works on the automatization of computational workflows in biomedical research, provides data managing tools and infrastructures that support the fast transfer of new research results into healthcare. A fundamental challenge of a digital healthcare environment is the growing amount of sensitive patient data, e.g., created by smart wearables or whole genome sequencing data. Handling and processing of such huge data sets in daily routine diagnostics requires new infrastructures and IT solutions. Therefore, the team is also working on large-scale IT and cloud solutions, in particular the de.NBI cloud. The Health Data team is located in both Berlin and Heidelberg. Please visit https://www.hidih.org/research/health-data for further information.

- ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium (2020). Pan-cancer Analysis of Whole Genomes, Nature, 578(7793), 82-93, doi: 10.1038/s41586-020-1969-6
- Yakneen, S.^§, Waszak, S.M., PCAWG Technical Working Group, Gertz, M., Korbel, J. O.^§, PCAWG Consortium (2020). Bulter enables rapid cloud-based analysis of thousands of human genomes. Nature Biotechnology, Epub ahead of print, doi: 10.1038/s41587-019-0360-3
- Ishaque, N.*, Abba, M.L.*, Hauser, C., Patil, N., Paramasivam, N., Huebschmann, D., Leupold, J.H., Balasubramanian, G.P., Kleinheinz, K., Toprak, U.H., Hutter, B., Benner, A., Shavinskaya, A., Zhou, C., Gu, Z., Kerssemakers, J., Marx, A., Moniuszko, M., Kozlowski, M., Reszec, J., Niklinski, J., Eils, J., Schlesner, M., Eils, R., Brors, B. & Allgayer, H.^§ (2018). Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer. Nature Communications, 9(1), 4782. doi: 10.1038/s41467-018-07041-z
- Gröbner, S.N.*, Worst, B.C.*, Weischenfeldt, J., Buchhalter, I., Kleinheinz, K., Rudneva, V.A., Johann, P.D., Balasubramanian, G.P., Segura-Wang, M., Brabetz, S., Bender, S., Hutter, B., Sturm, D., Pfaff, E., Hubschmann, D., Zipprich, G., Heinold, M., Eils, J., Lawerenz, C., Erkek, S., Lambo, S., Waszak, S., Blattmann, C., Borkhardt, A., Kuhlen, M., Eggert, A., Fulda, S., Gessler, M., Wegert, J., Kappler, R., Baumhoer, D., Burdach, S., Kirschner-Schwabe, R., Kontny, U., Kulozik, A.E., Lohmann, D., Hettmer, S., Eckert, C., Bielack, S., Nathrath, M., Niemeyer, C., Richter, G.H., Schulte, J., Siebert, R., Westermann, F., Molenaar, J.J., Vassal, G., Witt, H., Burkhardt, B., Kratz, C.P., Witt, O., van Tilburg, C.M., Kramm, C.M., Fleischhack, G., Dirksen, U., Rutkowski, S., Fruhwald, M., von Hoff, K., Wolf, S., Klingebiel, T., Koscielniak, E., Landgraf, P., Koster, J., Resnick, A.C., Zhang, J., Liu, Y., Zhou, X., Waanders, A.J., Zwijnenburg, D.A., Raman, P., Brors, B., Weber, U.D., Northcott, P.A., Pajtler, K.W., Kool, M., Piro, R.M., Korbel, J.O., Schlesner, M., Eils, R., Jones, D.T.W., Lichter, P., Chavez, L.^§, Zapatka, M.^§, Pfister, S.M.^§ (2018). The landscape of genomic alterations across childhood cancers. Nature, 559(7714), 321-327, doi: 10.1038/s41586-018-0167-2
- Reisinger, E.^§, Genthner, L., Kerssemakers, J., Kensche, P., Borufka, S., Jugold, A., Kling, A., Prinz, M., Scholz, I., Zipprich, G., Eils, R., Lawerenz, C., Eils, J. (2017). OTP: An automatized system for managing and processing NGS data. Journal of Biotechnology, 10(261), 53-62, doi: 10.1016/j.jbiotec.2017.08.006
- Raab, R., Kuderle, A., Zakreuskaya, A., Stern, A. D., Klucken, J., Kaissis, G., Rueckert, D., Boll, S., Eils, R., Wagener H., & Eskofier, B. M. (2023). Federated electronic health records for the European Health Data Space. Lancet Digit Health, 5(11), e840-e847. doi:10.1016/S2589-7500(23)00156-5
*these authors contributed equally. ^§corresponding author

Research group Eils - Team
Group Leader Project Management	Dr. Friedrich, Alexandra	alexandra.friedrich@bih-charite.de	Luisenstraße 65	030450543106
Office Manager	Hartung, Wiebke	wiebke.hartung@bih-charite.de	Luisenstraße 65	030450643088
Project Manager	Dr. Canitz, Carsten	carsten-joerg.canitz@charite.de	Luisenstraße 65	030450581070
Project Manager	Müller, Franziska	franziska.mueller@bih-charite.de	Luisenstraße 65	030450543085
Project Manager	Dr. Schubert, Vivien	vivien.schubert@charite.de	Luisenstraße 65	030450543144
Project Manager	Dr. Schütz, Tatjana	tatjana.schuetz@bih-charite.de	Luisenstraße 65	030450543151
Project Manager	Seidemann, Britta	britta.seidemann@bih-charite.de	Luisenstraße 65	030450543131
Project Manager	Wächter, Sarah	sarah.waechter@bih-charite.de	Luisenstraße 65	030450543139
Project Manager	Dr. Zeilinger, Katrin	katrin.zeilinger@bih-charite.de	Luisenstraße 65

Artificial Intelligence
Founding Director Center for Digital Health	Prof. Dr. Eils, Roland	roland.eils@charite.de	Luisenstraße 65	030450543084
Team Member	Bodur, Leylanur	leylanur.bodur@bih-charite.de	Luisenstraße 65
Team Member	Upmeier zu Belzen, Julius Valten	julius.upmeier@bih-charite.de	Luisenstraße 65	030450543119
Team Member	Wolf, Benedict	benedict.wolf@charite.de	Luisenstraße 65
Research Assistant	Hegselmann, Stefan	stefan.hegselmann@charite.de	Luisenstraße 65
Research Assistant	Prof. Dr. Müller-Riemenschneider, Falk	falk.mueller-riemenschneider@charite.de	Luisenstraße 65
Research Assistant	Wild, Benjamin	benjamin.wild@bih-charite.de	Luisenstraße 65
PhD Student	Rheude, Tillmann	tillmann.rheude@bih-charite.de	Luisenstraße 65
Student Assistant	Abou Ghaloun, Sedra	sedra.abou-ghaloun@bih-charite.de	Luisenstraße 65
Student Assistant	Arnoldt, Lucas	lucas.arnoldt@charite.de	Luisenstraße 65
Student Assistant	Do, Minh Duc	minh-duc.do@bih-charite.de	Luisenstraße 65
Student Assistant	Eckhoff, Leonard		Luisenstraße 65
Student Assistant	Herrmann, Luis Manuel	luis.herrmann@bih-charite.de	Luisenstraße 65
Student Assistant	Kittner, Paul	paul.kittner@charite.de	Luisenstraße 65
Student Assistant	Köhler, Kristin	kristin.koehler@bih-charite.de	Luisenstraße 65
Student Assistant	Nguyen, Khue Minh	khue.nguyen@bih-charite.de	Luisenstraße 65

Health Data
Group Leader Health Data
Group Leader Cloud & IT	Wagener, Harald	harald.wagener@bih-charite.de	Luisenstraße 65	030450543087
Cloud Developer	Braun, Martin	martin.braun@bih-charite.de	Luisenstraße 65	030450543107
IT	Mathis, Jakob	jakob.mathis@bih-charite.de	Luisenstraße 65
IT	Schneider, Stefan	stefan.schneider@bih-charite.de	Luisenstraße 65	030450543111
Group Leader Data Management	Dr. Twardziok, Sven	sven.twardziok@bih-charite.de	Luisenstraße 65
Data Manager	Dr. Jentsch, Marcel	marcel.jentsch@charite.de	Luisenstraße 65	030450543105
Bioinformatician	Dr. Schneider-Lunitz, Valentin	valentin.schneider-lunitz@bih-charite.de	Luisenstraße 65	030450543137
Software Developer	Strubel, Philipp	philipp.strubel@bih-charite.de	Luisenstraße 65	030450543095
Data Manager	Taron, Ulrike	ulrike-helene.taron@bih-charite.de	Luisenstraße 65	030450543135
Group Leader Medicine Informatics (MI)	Dr. Meyer zum Büschenfelde, Dirk	dirk.meyer-zum-bueschenfelde@charite.de	Luisenstraße 65	030450543145
Systemadministrator Cloud	Ten, Foo Wei	foo-wei.ten@bih-charite.de	Luisenstraße 65
Research Assistant	Kohler, Severin	severin.kohler@charite.de	Luisenstraße 65	030450543103
Research Assistant	Meixner, Maximilian	maximilian.meixner@bih-charite.de	Luisenstraße 65
Technical Writer	Schaak, Lisa	lisa.schaak@bih-charite.de	Luisenstraße 65
System Integration Trainee	Boshof, Max Jonas	max-jonas.boshof@charite.de	Luisenstraße 65
System Integration Trainee	Runde, Alma Philine Karolin	alma.runde@charite.de	Luisenstraße 65

Computational Oncology
Group Leader Computational Oncologie	Ishaque, Naveed, PhD	naveed.ishaque@bih-charite.de	Luisenstraße 65	030450543096
Research Assistant	Denkena, Johanna	johanna.denkena@charite.de	Luisenstraße 65	030450543116
Postdoc	Mackowiak, Sebastian, Dr.	sebastian.Mackowiak@bih-charite.de	Luisenstraße 65	030450543090
PhD Student	Han, Runbing	runbing.han@bih-charite.de	Luisenstraße 65
PhD Student	Malt, Alexander	alexander.malt@bih-charite.de	Luisenstraße 65	030450543125
PhD Student	Müller-Bötticher, Niklas	niklas.mueller-boetticher@bih-charite.de	Luisenstraße 65	030450543136
PhD Student	Jiang, Yiheng		Luisenstraße 65
PhD Student	Sahay, Shashwat	shashwat.sahay@charite.de	Luisenstraße 65	030450543118
PhD Student	Tiesmeyer, Sebastian	sebastian.tiesmeyer@charite.de	Luisenstraße 65	030450543117
Student Assistant	Orteba, Jakub		Luisenstraße 65

Medical Omics
Group Leader Medical Omics	Dr. Lukassen, Sören	soeren.lukassen@bih-charite.de	Luisenstraße 65	030450543102
Research Assistant	Jabareen, Nabil	nabil.jabareen@bih-charite.de	Luisenstraße 65	030450543134
Research Assistant	Yuan, Dongsheng	dongsheng.yuan@charite.de	Luisenstraße 65	030450543134
PhD Student	Liu, Ding Ming	dingming.liu@charite.de	Luisenstraße 65
Student Assistant	Kühn, Chantal	marie-chantal.kuehn@charite.de	Luisenstraße 65

Roland Eils

Prof. Dr. Roland Eils

Artificial Intelligence - ailslab

Computational Oncology

Health Data

Links

Digital Health

Roland Eils

Prof. Dr. Roland Eils

Artificial Intelligence - ailslab

Selected Publications Roland Eils, Artificial Intelligence

Computational Oncology

Selected Publications Naveed Ishaque, Computational Oncology

Health Data

Health Data

Selected Publications Health Data