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The Omics Core Facility of the BIH specializes in high-throughput technologies and the processing and analysis of clinical samples. A Genomics unit fully equipped with state-of-the-art machines for next-generation sequencing is being established as well as separate Proteomics and Metabolomics units equipped with up-to-date machinery.

For work with large amounts of data and analysis of clinical data, expertise in bioinformatics at MDC and Charité and in other research facilities in the Berlin area is being further broadened through a Bioinformatics unit with research groups and associated service teams under one roof. The necessary IT infrastructure and high-performance computing capacities are under construction.

New cryogenic storage facilities for the standardized collection and long-term storage of patient specimens are being created and databank systems harmonized. This BIH Biobank guarantees access to a comprehensive repository of clinical samples of defined and controlled quality.

Induced pluripotent stem cells (iPSCs) as in-vitro models of human disease are essential for translational medicine. At BIH, the Stem Cell Core Facility is being established for generating and characterizing iPSCs. Newly recruited research groups will add new expertise in stem cell biology and engineering to BIH.

Interoperability and Metabolomics

  • Metabolomics

    The BIH Metabolomics Platform pursues mass spectrometry metabolomics research with clear translational medicine potential.

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Genomics and Proteomics

  • Genomics

    The BIH / MDC Genomics Platforms offer professional NGS support for BIH users.

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  • Proteomics

    Mass spectrometry-based proteomics offers the possibility of measuring thousands of proteins in a single run and has fundamentally changed the way that biological systems are analyzed.

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Bioinformatics and IT

  • Bioinformatics

    The Core Unit Bioinformatics (CUBI) provides bioinformatics and data analysis expertise.

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  • IT-Services

    The IT Core Facility provides the essential IT services for BIH which includes the basic setup for the staff and researchers.

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Biobank and Stem Cells

  • Biobank

    The BIH Biobank Core Facility will store a wide range of different types of specimens collected in BIH research projects, cohort studies and trials.

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  • Stem Cells

    Pluripotent stem cells are unique tools for closing the gap between the identification of disease-causing molecules or cellular mechanisms and the development of suitable therapeutic approaches.

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Cytometry and Cell Harvesting

  • Cytometry

    The multi-parameter analysis of cells within a heterogeneous sample at the single cell level is one of the most important technology for understanding of biological relationships.

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  • Cell Harvesting

    The BCRT Cell Harvesting Lab (BCRT-CH) provides access to fully-characterized human tissue, which has been harvested during orthopaedic or trauma surgery in a standardized fashion.

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Bioportal Single Cell and Imaging Mass Spectrometry Unit

  • Bioportal Single Cells

    The BIH Bioportal Single Cells is part of the BIH Clinical Single Cell Sequencing (CSCS) pipeline, which connects relevant core facilities into an integrated service workflow.

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  • Imaging Mass Spectrometry Unit

    Our team is working to better understand and identify molecular processes, cellular factors, and changes that lead to the healing and disease of human tissues.

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Contact

Dr. Christian Hirsch

Scientific Coordinator Core Facilities

Contact information
Phone:+49 30 450 543 020
E-mail:christian.hirsch@bih-charite.de