Not only the DNA sequence – our genome – but also the 3D structure of our genome – the 'epi-genome' – is essential in determining the type and function of a cell. That's why the analysis of the epigenome facilitates deep insights into the developmental history of a cell and its current gene expression profile, but also allows deductions on its…

Research of Molecular Epidemiology Unit at the Berlin Institute of Health and the Charité is focused on epigenetic modifications that occur in close interaction between the individual genetic background and environmental exposure and potentially contribute to increased disease risks. Thereby, we are in particular interested to identify key events…