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Part of the Lecture Series "Frontiers in Translational Medicine - Scientific and Structural Challenges" on key questions of translation in medicine.

This page is only available in English.

BIH Lecture

BIH Lecture

How to avoid being mislead by the medical literature

The medical literature is fraught with potentially misleading findings and interpretations of findings.  In this presentation Gordon Guyatt will deal with three of them.  First, he will present evidence that funding of research influences the conclusions that authors draw from their data and suggest that clinicians should never read authors’ discussion of their own work but rather look to systematic reviews or guidelines from unconflicted sources.  Second, he will present the problems with surrogate outcomes, and how clinicians must wait for trials that demonstrate benefits on patient-important outcomes before prescribing new treatments.  Finally, he will show how randomized trials stopped early for benefit overestimate treatment effects, sometimes to a very large degree.

About the Speaker

Dr. Gordon Guyatt is a Distinguished Professor in the Department of Health Research Methods, Evidence and Impact, and the Department of Medicine at McMaster University.  He is a general internist who has been heavily involved in clinical research.  He has published over 1,500 papers in peer-reviewed journals; according to the Web of Science his work has been cited over 195,000 times.

In 1990, Dr. Guyatt coined the term ‘evidence-based medicine’ and since has provided leadership in developing the methods for evidence-based clinical decision making worldwide.  In 2011, Dr. Guyatt received Canada's highest award for civilians, an Officer of the Order of Canada. In 2013 was chosen as the Canadian Institute for Health Research Researcher of the Year and in 2016 he was inducted into the Canadian Medical Hall of Fame.  In 2022 he was honored by the Einstein Foundation for his contributions to improving the quality of medical research.


December 1, 2023
12:00 - 1:00 pm CET

Online via Zoom
The login data will be provided shortly before the event.

Please register here.


Caroline Wiesmeier


Telefon:+49 (0) 175 51 53 653