BIH Lecture with the Winner of the BIH Excellence Award for Sex and Gender Aspects in Health Research 2021 (Cancelled)
Part of the Lecture Series "Frontiers in Translational Medicine - Scientific and Structural Challenges" on key questions of translation in medicine. This time we welcome the winner of the BIH Excellence Award for Sex and Gender Aspects in Health Research in 2021.
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"From GWAS to novel treatment targets. Sex does matter in coronary artery disease."
Genome-wide association studies (GWAS) have identified over 300 loci associated with susceptibility to CAD. Consistent with other complex diseases, genetic discovery analyses in CAD have enabled insights into disease etiology and causal risk factors, facilitated the development of novel tools for predicting clinical risk, and identified novel therapeutic targets. The largest CAD meta-analysis to date, performed by Jeanette Erdmann and collaborators, identified the first associations that differed by sex. For none of these loci a causal link between SNP and specific genes have been established yet. Furthermore, there are no data that can explain the sex-specific effects of these loci.
About the Speaker
Jeanette Erdmann is a DZHK Professor and Director of the Institute for Cardiogenetics at the University of Lübeck, Germany. Honoring her achievements in the cardiovascular genetics field for the last 15 years she was elected as a member of the German National Academy of Sciences in 2021. The current 25 members of the Institute’s team are working towards a better understanding of the genetic causes of cardiovascular disease, especially coronary artery disease and myocardial infarction, using methods from bioinformatics and genetic epidemiology as well as cell and animal models. In 2017, she established a research group at the Institute of Cardiogenetics with the goal of developing therapeutic strategies for COL6-CMD, a rare neuromuscular disorder with which she diagnosed myself 10 years ago.
Registration
The lecture will be held online. Please register here.
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Recording
The BIH Lecture will be recorded for the documentation on our website.
Thank you for your cooperation!
Info
When
February 24, 2023
12:00 - 1:00 pm
How
online via Zoom.
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Registration
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