Architectured Biomedical Materials for Tissue Regeneration
Ansgar Petersen
Defects in musculoskeletal tissues, e.g. in consequence of a trauma, do not always heal spontaneously but require surgical intervention. Biomaterials implanted into the defect region have to potential to support the healing process. We investigate the interaction between cells, their surrounding extracellular matrix and biomaterials for the development of innovative treatment strategies. We design micro-environments that provide specific mechanical and geometrical signals that support endogenous healing cascades for an improved healing outcome.
Research focus
- Biomaterial architecture-guided cell function and extracellular matrix structure to induce endogenous healing cascades
- Surface curvature-controlled cell function, fate and organization
- Role of extrinsic (in vivo-like) mechanical loads in cell function & fate
- Spatial self-organization of cells and tissue patterning
- Tension in the extracellular matrix as a cell-instructive mechanical Parameter
Akkordeon
Vita Prof. Dr. Ansgar Petersen
CV
Professional development
- Since 2021: Professor of “Architectured Biomedical Materials for Tissue Regeneration” at the Berlin Institute for Health (BIH) | Charité – Universitätsmedizin Berlin
- Since 2012: Head of the “Cellular Biomechanics” research group at the Julius Wolff Institute | Charité – Universitätsmedizin Berlin
- 2008 – 2012 Research Fellow – Postdoctoral Researcher at the Julius Wolff Institute | Charité – Universitätsmedizin Berlin
- 2007 – 2008 Development Engineer at Matricel GmbH | Herzogenrath
- 2002 – 2007 Helmholtz Institute for Biomedical Engineering | RWTH Aachen University
Education
- 2002 – 2008 PhD in Biomedical Engineering | RWTH Aachen University
Thesis topic: “Fundamentals of electrically induced ice nucleation and its application in cryobiology” - 1995 – 2002 Master’s degree in Physics | RWTH Aachen University
Functions / offices
Spokesperson of the Berlin School for Regenerative Therapies
Member in Research Societies
- Deutsche Physikalische Gesellschaft (DPG)
- Deutsche Gesellschaft für Biomaterialien (DGBM)
- European Society for Biomaterials (ESB)
- European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS)
Reviewer for Scientific Publications
- Advanced Functional Materials
- Advanced Science
- Biomaterials
- Biophysical Journal
- Biotechnology and Bioengineering
- e Cells and Materials (eCM)
- Clinical Biomechanics
- Proceedings of the International Heat Transfer Conference
- Journal of Cinical Investigations
- Journal of Materials Science
- Materials Today
- Scientific Reports
- TERM
- Tissue Engineering
- Journal of Biomechanics
Reviewer for Research Proposals
- Deutsche Forschungsgemeinschaft (DFG)
- European Research Council (ERC) „ERC Frontier Research Grants“
- Bayerische Forschungsstiftung
- Swiss National Science Foundation
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