+++ We are sorry to inform that due to the current situation regarding the Coronavirus (SARS-Cov-2), we are forced to cancel the lecture of Prof. Zechner on 18 March 2020 +++
The Institute of Pharmacology and the Center for Cardiovascular Research (CCR) together with the Medical Clinic with a focus on Cardiology at the CVK of Charité – Universitätsmedizin Berlin invite you to the Cardiology Science Lunch Berlin. This time you can expect a lecture by Einstein BIH Visiting Fellow Professor Rudolf Zechner from the Institute of Molecular Biosciences at the University of Graz, Austria. He will talk about the physiology and pathophysiology of fat lipolysis.
Rudolf Zechner studies the mechanisms regulating lipid metabolism and causes of metabolic diseases. His team specifically focuses on fat-degrading enzymes called lipases. Discovery of adipose triglyceride lipase and the demonstration that this enzyme initiates fat catabolism in mice and humans overturned our understanding of the lipolytic pathway. More recently, Zechner's laboratory investigates how the breakdown of fat affects cellular signaling processes and cell function. Discoveries of the Zechner laboratory identified crucial links between fat catabolism, nuclear receptor signaling and heart function or the role of lipolysis in thermogenesis. Current work focuses on the functional impact of lipolysis in the pathogenesis of cancer-associated cachexia, a fatal wasting disease that is characterized by the unintended loss of body weight. Furthermore, the finding that pharmacological inhibition of adipose triglyceride lipase reduces high fat diet-induced obesity, glucose intolerance, and liver steatosis in mice, drives current efforts to probe the enzyme's potential as a therapeutic target to treat obesity-related metabolic disorders. Source: Website of the National Academy of Science
A registration is not required.
The Einstein BIH Visiting Fellow Program is a cooperation between the Stiftung Charité and the Einstein Foundation Berlin.