Preclinical Rethinking Webinar

Join the first seminar session with Randall J. Ellis, PhD, (Department of Biomedical Informatics, Harvard Medical School) and learn about the importance of pre-registrations and registered reports in preclinical research.

Ellis R. J. (2022). Questionable Research Practices, Low Statistical Power, and Other Obstacles to Replicability: Why Preclinical Neuroscience Research Would Benefit from Registered Reports. eNeuro, 9(4), DOI: 10.1523/ENEURO.0017-22.2022

In the second seminar session, Prof. Peter Loskill (Organ-on-Chip Research, University of Tübingen) will share his expertise on new approach methods (NAMs), with a particular focus on how microphysiological systems are advancing translational preclinical research.

In the third seminar, Dr. Vibeke Fosse (Department of Clinical Science, University of Bergen) will present a set of recommendations designed to enhance the robustness of preclinical methods in translational research for personalized medicine.

Fosse V. et al. (2023). Recommendations for robust and reproducible preclinical research in personalised medicine. BMC Med 21, 14. DOI:10.1186/s12916-022-02719-0

In the fourth session, Dr. Samuel Pawel (Epidemiology, Biostatistics and Prevention Institute, University of Zurich) will explore the concept of replicating null findings and present methods for evaluating their replication.

Pawel S. et al. (2023). Replication of "null results" – Absence of evidence or evidence of absence? eLife12:RP92311 DOI:10.7554/eLife.92311.2

In the fifth session, Dr. Christoph Conrad (Head of the Regulatory Support Unit, Berlin Institute of Health) will discuss key aspects of the regulatory landscape in preclinical research and Dr. Matthias Ocker (Head of Experimental Medicine, Tacalyx GmbH) will provide insights into the drug discovery process.

In the sixth session, Dr. Nikki Osborne (Responsible Research) and Dr. Nathalie Percie du Sert (NC3Rs) will give an overview of practical tools to support responsible and robust preclinical research.

Join the seventh session with Fanglian He, PhD, (founder of Bio-Protocol) to learn about methods and practices that improve research reproducibility in preclinical research.