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Michael Schmück-Henneresse

  • Targeted adaptation of a homing chemokine system for chimeric antigen receptor (CAR) T-cell products: CONAN (BMBF-funded)
  • T-cell migration and activation in autoimmunity, transplantation, and cancer
  • T-cell memory differentiation
  • Next generation regulatory and antigen-specific T-cell products
  • Gene-editing technologies to modify T cells (e.g. CRISPR-Cas)
  • Immunopathology issues related to CRISPR-Cas-mediated gene editing
  • Patient-derived (immunocompetent) cancer organoids as testing platform for immunotherapy