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The QUEST Center conducts projects in various areas.

The unique feature of our projects is their practical and translational focus: we seek to test new approaches in design, analysis and reporting in biomedical research, both preclinical and clinical, to improve translation of research results into clinical care.

The projects are, among others, identified and evaluated by so-called "meta-research", i.e. research on research. The focus of our projects lies on Open Science, Stakeholder Engagement, Incentives & Indicators as well as Quality Assurance (see filter below).



    With the Monitoring & Evaluation System COMPASS, BIH QUEST Center establishes a complex impact-oriented program evaluation of its activities.

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  • Quality Assurance Closed


    Organospecific Stratification in Covid-19 is part of the Forschungsnetzwerk "Nationale Universitätsmedizin". Among others, it deals with standards for organ models.

  • Quality Assurance Ongoing

    6R in Organ Model Research

    Advanced in vitro models have strong potential to complement or substitute animal experiments and improve translational research. We collaborate with organ model researchers to develop and implement measures towards robust organ models and enhance their broad acceptance via 6R strategies.

  • Quality Assurance Closed

    A qualitative study on the basis of expert interviews

    In response to what has been called the “reproducibility crisis”, institutions and granting agencies have begun to implement changes in how biomedical research activity is rewarded and funded. The aim of the project was to gain a better understanding of how different stakeholders view these ongoing reforms.

  • Open Science Ongoing


    ANONY-MED creates an ethically aligned, trustworthy AI toolbox for privacy-preserving data synthesis using generative AI methods like GANs and homomorphic encryption in healthcare. This advances AI models in radiology, cardiology, and stroke therapy, while ensuring transparency and robustness.

  • Quality Assurance Closed


    This project assesses how outcomes of registered clinical trials are changed over the course of the trial, and how these changes are reported.

  • Quality Assurance Closed


    BRAVO examines the extent to which Germany's medical faculties consider and promote various aspects of quality of biomedical research.

  • Quality Assurance Open Science Closed

    BUA Open Science Dashboards

    The project aims to include FAIR criteria in the Charité Metrics Dashboard and co-develop prototype open science dashboards for other research fields.

  • Quality Assurance Open Science

    BUA Open Science Magnifiers

    The project "Berlin University Alliance Open Science Magnifiers" continues and further develops the systematic monitoring of Open Science practices. This includes visualizations of indicators for open practices, as well as highlighting of specific best-practice examples.

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