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Cardiovascular Research

Metabolic Pathopyhsiology

Wolfram Döhner

We investigate clinical pathophysiological metabolic changes of muscle and fat tissue in chronic diseases. In clinical work, cardiovascular knowledge is combined with acute therapy and stroke rehabilitation. Our research is focused on metabolic pathophysiology, which leads to weight loss and loss of muscle mass, cachexia and sarcopenia in chronic diseases.

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Prof. Wolfram Döhner

Contact information
Address:BIH Centrum für Regenerative Therapien
Augustenburger Platz 1
13353 Berlin
Campus internal address: Föhrer Straße 15
E-mail:Wolfram.doehner@bih-charite.de

Research focus

  • Interdisciplinary complications in stroke

  • Metabolic regulation in acute and chronic disease and during rehabilitation

  • Muscle metabolism and function in stroke and post stroke rehabilitation

  • Cachexia, sarcopenia and frailty in disease, in rehabilitation and in in the elderly

  • Insulin resistance, energy metabolism, xanthine oxidase metabolism in cardiovascular disease

  • Peripheral vascular (endothelium) function

  • Clinical proof-of concept trials on metabolic interventions in patients with cardiovascular disease