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Prof. Hans-Peter Kiem

BIH Lecture

Novel Approaches To Targeting Hematopoietic Stem Cells for Ex Vivo and in Vivo Gene Therapy

Despite tremendous progress in the hematopoietic stem cell (HSC) gene therapy and gene editing field, there are a number of significant limitations to the availability and accessibility of these therapies. In my presentation, I will discuss how we can better target a more refined HSC population to significantly reduce the amounts of lentiviral vectors or gene editing reagents needed for the genetic engineering of HSCs. I will also discuss how we can make these therapies more portable and accessible by developing in vivo gene therapy approaches that would not require rare and highly sophisticated cell manufacturing facilities and thus could be more accessible and also available for patients in low and middle-income settings.

About the Speaker

Kiem is a world-renowned expert in stem cell gene therapy. His lab has developed gene therapy trials for Fanconi anemia, glioblastoma, and HIV. A major recent focus has been the development of in vivo gene therapy approaches using various delivery platforms including viral vectors and nanoformulations. He has had continuous NIH funding for the past 25 years and has published more than 300 manuscripts. Kiem was the inaugural recipient of the José Carreras/E. Donnall Thomas Endowed Chair for Cancer Research at the Fred Hutch from 2009 to 2014 and now holds the Stephanus Family Endowed Chair for Cell and Gene Therapy and is Director of the Stem Cell and Gene Therapy Program at Fred Hutch. In May of 2022 he assumed his role as president of the American Society of Gene and Cell Therapy.

Registration

The lecture will be held online via GoToMeeting. To participate in the lecture, please register here.
The registration will be open until maximal participant capacity is reached.

Login Information

Info

When
September 16, 2022
12:00 - 1:00 pm
  1:10 - 2:00 pm | Meet the Speaker-Session

How
online via GoToMeeting
The login data will be provided shortly before the event.

Registration
Please register here.
Registration is open until the maximum number of participants is reached.

Patricia Ebel

Koordinatorin Veranstaltungen | Redakteurin Online-Kommunikation

Kontaktinformationen
Telefon:+49 30 450 543 073
E-Mail:patricia.ebel@bih-charite.de