The objective of our research group is to acquire the basic knowledge necessary to develop new therapies against diseases affecting the liver. For that, we use stem cells to model embryonic development in vitro and to produce liver cells with an interest for cell therapy.

Bone is an interesting tissue from the researchers view as it is able to regenerate after injury. However, even today and with an adequate treatment 5-20% of all fractured patients experience a delayed or non-union.

The Integrative Vascular Biology Laboratory aims to unravel the fundamental principles and molecular/genetic regulation of functional vascular network formation in development and disease.

Tissues in the musculoskeletal system are exquisitely designed with superb mechanical properties. The tissues are also able to adapt to withstand changing mechanical conditions. The Computational Mechanobiology Group is focused on understanding these two exciting features. Using computer modeling techniques, we seek to understand the mechanical…

Our research focuses on molecular changes in the development of various tumors. We now want to use bioinformatic and experimental methods to better understand the early development of cancer in order to be able to intervene and prevent it in the long term.

Our motivation is to address fundamental biological questions of human immunology and translate them into innovative therapies. In this respect, the core interest of our laboratory lies in the discovery of new applications of antibodies and B cells to treat and prevent challenging human diseases.

The Potente laboratory focuses on the vasculature—the largest organ in the human body. We study how vascular networks develop and remodel and how their function becomes abnormal in disease states.

We investigate clinical pathophysiological metabolic changes of muscle and fat tissue in chronic diseases. In clinical work, cardiovascular knowledge is combined with acute therapy and stroke rehabilitation. Our research is focused on metabolic pathophysiology, which leads to weight loss and loss of muscle mass, cachexia and sarcopenia in chronic…

Genetic sequencing, an essential method in life science, is mainly driven by fluorescence imaging. In the advent of spatial imaging and in situ sequencing directly on cells and human tissues, we aim to apply latest deep learning and microscopic automation for translational medicine and molecular pathology. This includes fast optical imaging, single…