Integrative Vascular Biology
Holger Gerhardt
The Integrative Vascular Biology Laboratory aims to unravel the fundamental principles and molecular/genetic regulation of functional vascular network formation in development and disease.
The Integrative Vascular Biology Laboratory aims to unravel the fundamental principles and molecular/genetic regulation of functional vascular network formation in development and disease.
Our research focuses on molecular changes in the development of various tumors. We now want to use bioinformatic and experimental methods to better understand the early development of cancer in order to be able to intervene and prevent it in the long term.
Our motivation is to address fundamental biological questions of human immunology and translate them into innovative therapies. In this respect, the core interest of our laboratory lies in the discovery of new applications of antibodies and B cells to treat and prevent challenging human diseases.
The Hedtrich Lab strives to understand and tackle inflammatory and genetic diseases of human epithelia with a current focus on skin, lungs, and intestine. As we firmly believe that human-based models are critical to close the current translational gap in biomedical research, my lab’s research relies on complex human-based organ- and organ-on-chip…
The Potente laboratory focuses on the vasculature—the largest organ in the human body. We study how vascular networks develop and remodel and how their function becomes abnormal in disease states.
We investigate clinical pathophysiological metabolic changes of muscle and fat tissue in chronic diseases. In clinical work, cardiovascular knowledge is combined with acute therapy and stroke rehabilitation. Our research is focused on metabolic pathophysiology, which leads to weight loss and loss of muscle mass, cachexia and sarcopenia in chronic…
Genetic sequencing, an essential method in life science, is mainly driven by fluorescence imaging. In the advent of spatial imaging and in situ sequencing directly on cells and human tissues, we aim to apply latest deep learning and microscopic automation for translational medicine and molecular pathology. This includes fast optical imaging, single…