Program Overview

The funding program supports the development of novel therapeutics (small molecules, biologics, ATMPs, gene therapy), medical devices and diagnostics for unmet medical needs, as well as repurposing of existing drugs for new indications. The program aims at the validation of research findings and translation into therapies, products or services. Only Scientists and Clinicians from BIH, Charité and MDC are eligible to apply.

We offer funding and mentoring to de-risk projects with high potential impact, addressing critical unmet medical needs that have a competitive advantage over current gold standard therapies/solutions.

Selected projects become part of the SPARK-BIH mentoring program. We …

… help you to establish Intellectual Property and to learn what translation is all about.
… organize regular meetings for SPARKees (by invitation only).
… offer education in different formats.
… organize workshop targeted at needs of SPARK projects (e.g. GLP, MDR, Business Model).

Find out more information about the SPARK-BIH program

Two tracks of funding

The funding program consists of two different tracks and funding is strictly milestone-based:

  • Track 1 projects are usually earlier in the development timeline and track 1 funding covers projects with a budget of up to 50k € for one year.
  • Track 2 projects are further along the development timeline and must meet strict requirements regarding intellectual property rights and market access strategies. Funding covers projects with a financial need of more than 50k € for up to two years.

Some examples of past and current projects include unmet needs in pediatric, neglected or orphan diseases, cardiovascular, oncology, inflammatory, respiratory, neurological, autoimmune indications and infectious disease. We will consider small molecule, biologics, medical device, as well as diagnostic applications from all medical disciplines and other indications of serious unmet medical need.


The BIH seeks to increase the diversity of its funding programs. Women, individuals from underrepresented racial and ethnic groups, as well as individuals with disabilities are especially encouraged to apply for BIH programs.