Metabolomics is the analysis of small molecules called metabolites in biological cell, tissue, organ, or organism. These small molecules and their interaction in a biological system is known as the metabolom. Metabolomics analyses can lead to new understanding of complex metabolic pathways and can suggest new hypothesis on mechanisms, treatments and prognoses for diseases. Metabolomics aims to provide a snapshot at a specific point in time and in combination with other –omics technologies bridges from genotype to phenotype.
The mammalian body is host to a large number of individual metabolites, spanning a wide range of physicochemical properties. To be able to measure a broad range of these metabolites from just one sample presents some challenges. The BIH Metabolomics Platform is equipped with some of the latest range of mass spectrometers and separation technologies to enable world class research.